解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::One of the major goals of evo-developmentalists is to understand how the genetic mechanisms controlling embryonic development have evolved to create the current diversity of bodyplans that we encounter in the animal kingdom. Tyrosine kinase receptors (RTKs) are transmembrane receptors present in all metazoans known to...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2008.00299.x
更新日期:2009-01-01 00:00:00
abstract::orthodenticle (otd) genes are found throughout the animal kingdom and encode well-studied homeodomain transcription factors that share conserved functions in cephalization, head segmentation, brain patterning, and the differentiation of photoreceptors. Otd proteins have been proposed as ancestral key players in anteri...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2008.00283.x
更新日期:2008-11-01 00:00:00
abstract::We analyzed a comprehensive data set of ossification sequences including seven marsupial, 13 placental and seven sauropsid species. Data are provided for the first time for two major mammalian clades, Chiroptera and Soricidae, and for two rodent species; the published sequences of three species were improved with addi...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2008.00267.x
更新日期:2008-09-01 00:00:00
abstract::The larval skeletons of sea urchins show considerable morphological diversity, even between closely related species, although the evolutionary history and functional significance of this diversity are poorly understood. To infer the evolutionary history of the skeletal morphology, we focused on echinometrid species fo...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2008.00277.x
更新日期:2008-09-01 00:00:00
abstract::The N-terminal region of human HOXA13 has seven discrete polyalanine tracts. Our previous analysis of these tracts in multiple major vertebrate clades suggested that three are mammal-specific. We now report the N-terminal HOXA13 repetitive tract structures in the monotreme Tachyglossus aculeatus (echidna). Contrary to...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2008.00254.x
更新日期:2008-07-01 00:00:00
abstract::The expression of GpANTL1, a homolog of AINTEGUMENTA (ANT) found in the gymnosperm Gnetum parvifolium, was analyzed by RT-PCR and in situ hybridization. GpANTL1 was expressed in the leaf primordia, root tips, and young ovules. In the ovulate axis, expression was detected as four distinct rings around the outer, middle...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2008.00237.x
更新日期:2008-05-01 00:00:00
abstract::Onthophagus taurus is a polyphenic beetle in which males express alternative major (horned) and minor (hornless) morphologies largely dependent on larval nutrition. O. taurus was originally limited to a Turanic-European-Mediterranean distribution, but became introduced to several exotic regions in the late 1960s. Usin...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2008.00224.x
更新日期:2008-03-01 00:00:00
abstract::Most bilaterian animals have evolved a through gut that is regionally specialized along the anterior-posterior axis. In the polychaete annelid, Capitella sp. I, the alimentary canal is subdivided into a buccal cavity, pharynx, esophagus, midgut, and hindgut. Members of the Fox and GATA families of transcription factor...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2007.00216.x
更新日期:2008-01-01 00:00:00
abstract::Asymmetric cell divisions are a crucial mode of cell fate specification in multicellular organisms, but their relative contribution to early embryonic patterning varies among taxa. In the embryo of the mollusc Ilyanassa, most of the early cell divisions are overtly asymmetric. During Ilyanassa early cleavage, mRNAs fo...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2007.00194.x
更新日期:2007-11-01 00:00:00
abstract::"Hormone manipulation" is being used increasingly in evo-devo studies as the sole or primary technique to investigate the regulation of insect polymorphism by hormones, most notably juvenile hormone (JH). This manuscript critically evaluates the limitations and strengths of this indirect method for inferring aspects o...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2007.00181.x
更新日期:2007-09-01 00:00:00
abstract::Reef-building scleractinian corals widely engage in symbiotic relationships with Symbiodinium dinoflagellates (zooxanthellae), which reside inside cells of the gastrodermis. In most cases, sexually produced larvae acquire their symbionts from the environment in the early developmental stages preceding settlement; howe...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2007.00173.x
更新日期:2007-07-01 00:00:00
abstract::The origin of the turtle plastron is not known, but these nine bones have been homologized to the exoskeletal components of the clavicles, the interclavicular bone, and gastralia. Earlier evidence from our laboratory showed that the bone-forming cells of the plastron were positive for HNK-1 and PDGFRalpha, two markers...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2007.00159.x
更新日期:2007-05-01 00:00:00
abstract::Ontogeny often provides the most compelling evidence for primary homology in evolutionary developmental studies and is critical to interpreting complex structures in a phylogenetic context. As an example of this, we document the ontogenetic development of the caudal skeleton of Caranx crysos by examining a series of c...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2007.00148.x
更新日期:2007-03-01 00:00:00
abstract::The way in which novelties that lead to macroevolutionary events originate is a major question in evolutionary biology, and one that can be addressed using the fire salamander (Salamandra salamandra) as a model system. It is exceptional among amphibians in displaying intraspecific diversity of reproductive strategies....
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2006.00141.x
更新日期:2007-01-01 00:00:00
abstract::Repeated tooth initiation occurs often in nonmammalian vertebrates (polyphyodontism), recurrently linked with tooth shedding and in a definite order of succession. Regulation of this process has not been genetically defined and it is unclear if the mechanisms for constant generation of replacement teeth (secondary den...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2006.00118.x
更新日期:2006-09-01 00:00:00
abstract::The morphogenesis of a gut from the endoderm has been well studied among the animal kingdom and is also well described in the nematode Caenorhabditis elegans. But are there other ways to build a nematode intestine? Sulston et al. (1983) described a different intestinal cell lineage in the species Panagrellus redivivus...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2006.00108.x
更新日期:2006-07-01 00:00:00
abstract::LEAFY HULL STERILE1 (LHS1) is an MIKC-type MADS-box gene in the SEPALLATA class. Expression patterns of LHS1 homologs vary among species of grasses, and may be involved in determining palea and lemma morphology, specifying the terminal floret of the spikelet, and sex determination. Here we present LHS1 expression data...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2006.00100.x
更新日期:2006-05-01 00:00:00
abstract::Astacin-like metalloproteases are ubiquitous in the animal kingdom but their phylogenetic relationships and ancient functions within the Metazoa are unclear. We have cloned and characterized four astacin-like cDNAs from the marine hydroid Hydractinia echinata and performed a database search for related genes in the dr...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2006.00092.x
更新日期:2006-03-01 00:00:00
abstract::How do proteins evolve while maintaining their function? Previous studies find a highly stringent structure/function relationship between the Drosophila melanogaster testis-specific tubulin beta2 and the spermtail axoneme, such that small changes in the beta2 protein render it unable to generate a motile axoneme. This...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2006.05072.x
更新日期:2006-01-01 00:00:00
abstract::When approaching the study of terminal growth and segmentation, comparative morphology provides an important guide to formulate questions. There are often problems in unambiguously identifying the axis along which we wish to study terminal (often, actually, subterminal) growth, especially when the trunk axis is poster...
journal_title:Evolution & development
pub_type: 杂志文章,评审
doi:10.1111/j.1525-142X.2005.05060.x
更新日期:2005-11-01 00:00:00
abstract::Apical organs are a well-known structure in almost all ciliated eumetazoan larvae, although their function is poorly known. A review of the literature indicates that this small ganglion is the "brain" of the early larva, and it seems probable that it represents the brain of the ancestral, holopelagic ancestor of all e...
journal_title:Evolution & development
pub_type: 杂志文章,评审
doi:10.1111/j.1525-142X.2005.05051.x
更新日期:2005-09-01 00:00:00
abstract::Jaw shedding and replacement of Diopatra aciculata (Onuphidae, Eunicida), by the same process as arthropod molting, involving apolysis and ecdysis, is described here. These observations suggest that molting has either evolved convergently in eunicidan polychaetes and ecdysozoans or it was present in the last ecdysozoa...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2005.05039.x
更新日期:2005-07-01 00:00:00
abstract::An ongoing challenge to evolutionary developmental biology is to understand how developmental evolution on the level of populations and closely related species relates to macroevolutionary transformations and the origin of morphological novelties. Here we explore the developmental basis of beetle horns, a morphologica...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2005.05020.x
更新日期:2005-05-01 00:00:00
abstract::Phenotypes of organisms are not determined completely genetically, but vary according to environmental factors (phenotypic plasticity). Some organisms express several discrete adaptive phenotypes (polyphenism). Social insects possess a few types of individuals (castes) in their colonies, to which specific tasks are al...
journal_title:Evolution & development
pub_type: 杂志文章,评审
doi:10.1111/j.1525-142X.2005.05014.x
更新日期:2005-03-01 00:00:00
abstract::The sex determination pathway is different between Drosophila melanogaster and Bombyx mori in the initial signal. Here we show evidence that the sex determination pathway in B. mori is similar to that of D. melanogaster at the level of the terminal regulator, doublesex (dsx), which is essential for the proper differen...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2005.05007.x
更新日期:2005-01-01 00:00:00
abstract::Evolutionary transitions in larval nutritional mode have occurred on numerous occasions independently in many marine invertebrate phyla. Although the evolutionary transition from feeding to nonfeeding development has received considerable attention through both experimental and theoretical studies, mechanisms underlyi...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2004.04047.x
更新日期:2004-11-01 00:00:00
abstract::Molecular and morphological data sets have yielded conflicting phylogenies for the Metazoa. So far, no general explanation for the existence of this conflict has been suggested. However, I believe that a neglected aspect of metazoan cladistics has introduced a systematic and substantial bias into morphological phyloge...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142X.2004.04045.x
更新日期:2004-09-01 00:00:00
abstract::Geophilomorph centipedes exhibit a number of unique characteristics that make them of particular developmental and evolutionary interest. Segment numbers in geophilomorphs are higher than in any other centipedes, ranging from 27 to 191. They may be constant within a species, presenting in extreme form the "counting" p...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1111/j.1525-142x.2004.04016.x
更新日期:2004-03-01 00:00:00
abstract::The mocker swallowtail, Papilio dardanus, has a female-limited polymorphic mimicry. This polymorphism is controlled by allelic variation at a single locus with at least 11 alleles. Many of the alternative morphs are accurate mimics of different species of distasteful butterflies. Geneticists have long been interested ...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2003.03063.x
更新日期:2003-11-01 00:00:00
abstract::The mouse mandible has long served as a model system for studying the development and evolution of complex morphological structures. We used the methods of geometric morphometrics to reassess the hypothesis that the mandible consists of two separate modules: an anterior part bearing the teeth and a posterior part with...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2003.03057.x
更新日期:2003-09-01 00:00:00
abstract::Homeobox transcription factors are commonly involved in developmental regulation in diverse eukaryotes, including plants, animals, and fungi. The origin of novel homeobox genes is thought to have contributed to many evolutionary innovations in animals. We perform a molecular phylogenetic analysis of cnox2, the best st...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2003.03041.x
更新日期:2003-07-01 00:00:00
abstract::The phylogenetic positions of frogs, salamanders, and caecilians have been difficult to establish. Data matrices based primarily on Paleozoic taxa support a monophyletic origin of all Lissamphibia but have resulted in widely divergent hypotheses of the nature of their common ancestor. Analysis that concentrates on the...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2003.03038.x
更新日期:2003-05-01 00:00:00
abstract::The vertebrate Zic gene family encodes C2H2 zinc finger transcription factors closely related to the Gli proteins. Zic genes are expressed in multiple areas of developing vertebrate embryos, including the dorsal neural tube where they act as potent neural crest inducers. Here we describe the characterization of a Zic ...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2003.03020.x
更新日期:2003-03-01 00:00:00
abstract::Understanding the genetic and molecular mechanisms of morphological evolution is one of the greatest challenges in evolutionary biology. Sexually dimorphic traits, which often evolve at a high rate due to their involvement in mate choice and sexual selection, present unique opportunities for investigating changes in d...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2002.02017.x
更新日期:2002-07-01 00:00:00
abstract::Organizers of the symposium Starting from Fins: Parallelism in the Evolution of Limbs and Genitalia intended it 1) to begin debates and discussions about parallelism, serial homology and transitions in development, as well as evolution of gene function and theories of origins and 2) to examine closely the potential si...
journal_title:Evolution & development
pub_type:
doi:10.1046/j.1525-142x.2002.01067.x
更新日期:2002-03-01 00:00:00
abstract::The full-length sequence and developmental expression of amphioxus AmphiFoxE4 are described. Transcripts of the gene are first detected in the pharyngeal endoderm, where the club-shaped gland is forming and subsequently in the definitive gland itself. AmphiFoxE4 is closely related to vertebrate genes encoding the thyr...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2002.01057.x
更新日期:2002-01-01 00:00:00
abstract::Using the Hawaiian acorn worm, Ptychodera flava, we began molecular studies on the development of hemichordates, a phylum previously unstudied at this level. Here we review results garnered from the examination of a few specific genes selected to help understand the evolution of vertebrate structures. These studies su...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2001.01050.x
更新日期:2001-11-01 00:00:00
abstract::To identify the mechanisms by which molecular variation is introduced into developmental systems, microevolutionary approaches to evolutionary developmental biology have to be taken. Here, we describe the molecular and developmental characterization of laboratory strains of the nematode genus Pristionchus, which lays ...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2001.003004229.x
更新日期:2001-07-01 00:00:00
abstract::In Insecta and malacostracan Crustacea, neurons in the ventral ganglia are generated by the unequal division of neuronal stem cells, the neuroblasts (Nbs), which are arranged in a stereotyped, grid-like pattern. In malacostracans, however, Nbs originate from ectoteloblasts by an invariant lineage, whereas Nbs in insec...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2001.003003154.x
更新日期:2001-05-01 00:00:00
abstract::The structural diversity of gastropod veliger larvae offers an instructive counterpoint to the view of larval forms as conservative archetypes. Larval structure, function, and development are fine-tuned for survival in the plankton. Accordingly, the study of larval adaptation provides an important perspective for evol...
journal_title:Evolution & development
pub_type: 杂志文章
doi:10.1046/j.1525-142x.2001.01003.x
更新日期:2001-01-01 00:00:00